Scientists have concluded that copper oxide nanoparticles are significantly more toxic than their bulk counterpart to human cells in vitro.
The researchers examined the effects of nanoparticles on cells from the lining of the human lung, and found that the nanoparticles enter the cells where they cause DNA damage and changes in essential cell components including the mitochondri. In contrast, bulk particles showed much lower toxicity to the cells, according to the researchers.
The authors state that the study provides useful data for understanding the transport and toxicity of metal oxide nanoparticles in human cells. It is published in the journal Chemical Research in Toxicology.
Fonte: Chemical Watch